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Its effects on angiogenesis, while potentially helpful for healing, raise unresolved questions about its action in the presence of abnormal tissue growth

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Guanylate Cyclase Activation : The nitric oxide produced from L-citrulline activates guanylate cyclase, which synthesizes cyclic guanosine monophosphate (cGMP) that directly signals cardiovascular smooth muscles to relax and promote healthy blood flow

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