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Methods and analysis The study is a randomised, placebo-controlled, single-blind, clinical trial with two parallel groups which are administered mecobalamin (vitamin B 12 ) or placebo over 12 weeks

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Side‑effects are mild and transient—drowsiness, brief headache, vivid dreams, or occasional injection‑site irritation—without tolerance or dependence Potential side effects include injection site irritation, headache, vivid dreams, and hormone‑related effects