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[DOI] [PMC free article] [PubMed] [Google Scholar] Dublin S., Jackson M.L., Nelson J.C., Weiss N.S., Larson E.B., Jackson L.A

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Mitochondrial oxidative stress and persistent antigenic stimulation promote the exhaustion of cytotoxic T cells, which is a state of dysfunction that is often observed in the tumor microenvironment [99,100]