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10.1161/CIRCULATIONAHA.118.034532 48

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Experimental evidence has shown that ginsenosides can promote the expression of multidrug resistance proteins (MRPs) 1 and 3, upregulate Nrf2 and its target genes, inhibit the ERK and JNK MAPK pathways, reverse CYP2E1 overexpression, enhance antioxidant stress response, and exert hepatoprotective effects [73]