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Specifically, after only 1 week of exposure to a WD (44.9% kcals from fat) at 3 weeks old, WD mice consumed significantly more calories from relative to controls when given a macronutrient choice test, which included options for a high fat diet, a high carbohydrate diet, or high protein diet in adulthood for 10 days

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However, DHAR shares significant sequence similarity with chloride intracellular channels (CLICs) (~26% identity and ~46% similarity) and the omega-class glutathione S-transferase (GSTO) (~21% identity and 35% similarity)