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What sets B12 deficiency apart from other causes of hair loss is its often subtle onset, with symptoms like fatigue, numbness, and pale skin overshadowing its effect on hair

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Angiogenesis endpoints are the most-replicated readouts in the literature — tube formation, VEGFR2 expression and nitric-oxide-pathway markers — and the standard design pairs them with a functional repair measure in the same model so that mechanism and outcome are linked rather than inferred