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Recent studies indicate that radiation exposure increases intracellular iron concentration by dampening the iron-sulfur center-containing proteins

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In a study of myeloma, sophocarpine triflorohydrazone was found to inhibit KRASA12 and AMO-1 myeloma cell proliferation by promoting the expression of proapoptotic proteins and activation of Notch3-p53 signaling (Wang et al., 2021e)