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We use the Reed-Nijhout model further to confirm that if the trans-sulfuration pathway is blocked—a “cysteine-block,” as it were—GSH does not rise even if Hcy is elevated (Figure 5B)

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Specifically, lithium treatment ameliorated adverse effects of Al on brain ultrastructure (Bhalla et al., 2010a), acetylcholinesterase and monoamine oxidase activity, as well as brain dopamine and serotonin levels (Bhalla et al., 2010b)