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Within each complex, the miRNA pairs to target RNAs, and AGO provides effector function while also protecting the miRNA from cellular nucleases 2,3,4,5
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Rare serious Botox complications include allergic reactions manifesting as rash, itching, or breathing difficulties requiring immediate medical attention, systemic botulism symptoms from toxin spread beyond injection site (extremely rare with cosmetic doses), and vision problems from periocular injections affecting eye muscles