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In addition to the classic hormones and neurotransmitters (adrenaline and glucocorticoids), stress induces the release of other mediators such as neuropeptides (substance P (SP) and neurotensin), cytokines, growth factors, and neurotransmitters (acetylcholine, serotonin, and dopamine), that are produced by nerve terminals or by endocrine glands

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One mechanism through which GLP-1 receptor agonists like Ozempic exert their therapeutic effects is by slowing gastric emptying , though this effect may attenuate over time