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It is therefore entirely plausible that chronic saturation of this receptor complex by UMFA could interfere with the reuptake and retention of their respective ligands, including holoTC and vitamin B-12, and this effect could be accentuated in individuals with renal insufficiency
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Wikipedia says that avobenzone loses 36% of its UV-absorption capacity after just one hour of sunlight (yep, this is one of the reasons why sunscreens have to be reapplied after a few hours)
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