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These observations suggest that the loss of endothelial cell antithrombotic function combined with the induction of a procoagulant state may contribute to the vascular disorders linked to moderate hyperhomocysteinemia

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Eyelid surgery: If the puffiness of eyelids is giving a dark appearance, your eye doctor may refer you to an oculoplastic surgeon who operates on the eyelids, where extra or loose skin is tightened for a normal appearance, a procedure known as blepharoplasty that reduces the dark appearance