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Furthermore, even while it is well established that betaine aids in the creation of various significant mediates, including glutamate, ALA, methionine, and glycine, it may also limit cell development at high concentrations

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In these cases, treatment should be initiated as soon as possible.[] The etiology of vitamin B12 deficiency typically includes malabsorption-related causes such as autoimmune gastritis (pernicious anemia), celiac disease, inflammatory bowel disease, surgical gastrectomy, gastric bypass, and ileal resection