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MMP-13 has also been observed in IBD patients, where the protease was increased in the inflamed tissue compared to non-inflamed areas [104]
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Because GHK is involved in tissue remodeling, wound repair, and the regulation of copper — a cofactor for many enzymes — researchers have long hypothesized that this age-related drop contributes to slower healing and reduced regenerative capacity in skin and, potentially, in hair follicles
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