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However, in a similar anatomical study of neurons in the locus coeruleus little or no loss of receptors was found after chronic morphine treatment (Van Bockstaele and Commons, 2001), but acute administration of morphine did induce internalization in the dendrites of neurons in the nucleus accumbens when measured with immuno-electron microscopy (Haberstock-Debic et al., 2003)

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for example, the interactive human phosphatase–substrate network contains now a ‘highlight node’ function for phosphatases, which includes the visualization of neighbors in the network