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In this assay, we immobilized biotinylated SARS-CoV-2 spike protein receptor-binding domain (RBD) or the Nucleoprotein (N) on streptavidin beads to detect specific antibodies from patient plasma (Fig
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These pro-inflammatory cytokines are recognized for modulating nociceptor sensitivity, synaptic plasticity, and neuroendocrine regulation, and their upregulation may underlie the widespread pain, fatigue, and sleep disturbances observed in fibromyalgia [47]
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