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Although a useful neoplasia biomarker, it is not known whether increased GSTP1 expression directly influences carcinogenesis, or is simply a bystander effect, where expression of this highly inducible gene is increased as part of the adaptive response mounted by the neoplastic cell

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As also observed for FOXO4 FH binding, the R 1 relaxation rates of p53 1–94 remained unaltered in presence of FOXO4-DRI (Supplementary Fig