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The subsequent cysteamine report by Szabo in the Lancet revealed the dopamine and gastric acid hypersecretion background, meaning that it became a seminal dopamine paper[86]
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Nrf2 regulates glutathione metabolism not only through the induction of enzymes in glutathione synthesis (e.g., GCLC, GCLM, GS) but also through the expression of enzymes that are responsible for glutathione utilization and redox cycling reduction (e.g., GR, SOD1, catalase, and several GPxs and GSTs) [90]