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The effects of vitamin B12 supplementation in pregnancy and postpartum on growth and neurodevelopment in early childhood: Study Protocol for a Randomized Placebo Controlled Trial - PMC

Due to their diverse colour expression and many proposed health effects 3 , their industrial adoption as natural colourants and bioactive compounds in the food, nutraceutical and cosmetic industries is progressively growing 4,5

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In pooled STEP 1-3 data on the 2.4 mg dose, nausea occurred in 43.9% (vs 16.1% placebo), diarrhea in 29.7% (vs 15.9%), vomiting in 24.5% (vs 6.3%), and constipation in 24.2% (vs 11.1%)