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Glutamate/GABA/glutamine ratios in intact and ischemia reperfusion challenged rat brain subregions, the effect of ischemic preconditioning | Metabolic Brain Disease | Springer Nature Link

The 2001 Heffernan study remains the most frequently cited source, and it was conducted in mice, not people (1)

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FIGURE 1 2 Signaling pathways in TCM intervening the pathological progression of DCM 2.1 TGF-β/Smad signaling pathway Excessive extracellular matrix deposition in the diabetic heart is associated with overexpression of transforming growth factor-β1 (TGF-β1) and connective tissue growth factors, which can cause cardiac fibrosis and damage the structure and function of the heart