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FIGURE 5 Concluding Remarks Radiation exposure to key endocrine organs (e.g., hypothalamus, pituitary, thyroid, and gonads) places cancer survivors at the highest risk of developing an endocrine abnormality over time, these endocrinopathies can develop decades following cancer treatment (Sklar et al., 2018), and are also observed in survivors treated with radiation to the head, neck, or pelvis ( in vivo and in vitro experiments is necessary
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