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Senescent cells promote tissue NAD(+) decline during ageing via the activation of… [PMID: 33199924] Laboratory literature summary: Senescent cells promote tissue NAD(+) decline during ageing via the activation of CD38(+) macrophages

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NAD+ (nicotinamide adenine dinucleotide) is a critical cofactor for mitochondrial energy production and sirtuin activation—proteins that regulate cellular aging, inflammation, and fat metabolism