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Simplified scheme for the metabolism of acrolein. GSH: glutathione,... | Download Scientific Diagram
[DOI] [PubMed] [Google Scholar] 175.Kuck J.F.R., KUCK K.D
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In AD (eczema), the skin's barrier defect is partly due to cytoskeletal‐junctional alterations: chronic Th2 inflammation (high IL‐4/IL‐13) downregulates key junction proteins (like claudin‐1) and loosens TJs, while repeated scratching triggers Ca ++ ‐dependent actomyosin contraction in epidermal cells
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