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Loss of MYMS1 in HSCs disrupts iron hemostasis and results in increased ferroptosis, which could be rescued with ferroptosis inhibitors such as liproxstatin-1 47
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Based on these observations, we speculate that Bhlhe40 induces Phb2 expression in early-anagen HG, thereby facilitating the interaction between PHB2 and LC3 to instigate mitophagy, eliminating damaged mitochondria accumulated in telogen
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