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Retromer has previously been linked to the γTuRC through its accessory protein ANKRD50 50 , and endosomal dynamics and endosomal cargo retrieval and recycling are heavily reliant on plus-end and minus-end directed microtubule motor proteins 118,119,120
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They will also monitor whether more breakthrough infections — which overwhelmingly have only caused mild outcomes so far — lead to more serious outcomes like hospitalization or death, a sign that boosters or even Omicron-specific vaccines might be needed to combat the variant
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