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doi: 10.1016/j.intimp.2016.08.006

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Consequently, UHRF1 has emerged as a novel therapeutic target, with proof‐of‐concept studies demonstrating that its pharmacological stabilization by compounds like Ryuvidine can ameliorate arthritis in preclinical models, validating a new strategy aimed at reinforcing endogenous suppressive epigenetic mechanisms [339, 342]