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Administering peptides through the nasal cavity eliminates the need for needles, ensuring a pain-free and hassle-free experience
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Notably, TGR5 agonism reduces pro-inflammatory cytokines, including IL-6, IFN-γ, and TNF-α, while enhancing anti-inflammatory IL-10 production (126, 127), and promotes macrophage polarization toward an anti-inflammatory phenotype (126, 127) ( Figure 2 )
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