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WADA Prohibition The World Anti-Doping Agency explicitly prohibits AOD-9604 for competitive athletes⁹: Listed under Section S0 (Non-Approved Substances) and S2.2.3 (Growth Hormone Fragments) Prohibited at all times (both in-competition and out-of-competition) No Therapeutic Use Exemptions (TUEs) available Detection methods developed and implemented in anti-doping laboratories worldwide WADA’s 2013 statement clarified that AOD-9604 “is a substance still under pre-clinical and clinical development and has not been approved for therapeutic use by any government health authority in the world.” Research Classification: AOD-9604 is available only for laboratory research use
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Human translation timelines are less defined due to limited clinical data, but based on pharmacokinetic principles and the upstream nature of NNMT inhibition, expect detectable metabolic shifts within 6–8 weeks if dosing and purity are appropriate