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The Genetics of Psoriasis, Psoriatic Arthritis and Atopic Dermatitis

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BACH1 forms heterodimers with small MAF proteins and recruits transcriptional corepressor complexes [nucleosome remodeling and deacetylase (NuRD), switch‐insensitive 3a (SIN3A), or switch/sucrose nonfermentable (SWI/SNF)] to the µLCR of the β‐globin gene, thus inhibiting the β‐globin gene expression