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There remains an issue with the slow active transfer of thiamine across the blood-brain barrier, which can be alleviated using higher doses to encourage passive transfer
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Size:4 Fluid oz
If this occurs, slight dose adjustment (increasing by 50mcg if not already at 500mcg) may help
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![PDF] Safety and Metabolism of AOD9604, a Novel Nutraceutical Ingredient for Improved Metabolic Health](https://figures.semanticscholar.org/3dfd33b87b7a620653288e23e2a1afe5b3bdaab3/2-Table1-1.png)
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