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For instance, in a placebo-controlled, double-blinded, randomized, phase 2 study (NCT03840005), the effect of Ursodeoxycholic acid (UDCA) on mitochondrial bioenergetics was found to be well tolerated in control and PD patients and evidenced increased ATP hydrolysis along with improved motor symptoms

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ImageJ software was used to generate images and quantify percentage of live and dead biofilm cells for biovolume