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Compared to pre-injection baselines, MM-associated parameters of CD4 + T cells, including naive CD4 + T cells (CD4 + Tn-MM), effect CD4 + T cells (CD4 + Te-MM), central memory CD4 + T cells (CD4 + Tcm-MM), and effector memory CD4 + T cells (CD4 + Tem-MM), exhibited significant decreases at all post-treatment time points (all p 4 and those with an NRS score ≤ 4

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