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For example, the signaling kinase PKGIα is activated upon dimerization which is enforced when a disulfide bond is formed between the same Cys residue (Cys42 and Cys42′) on two different subunits (implying the oxidation of Cys42 in one subunit to sulfenic acid, then condensation with another subunit as the other Cys42′ thiol group approaches) [115]
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