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PSAT1 modRNA induces cardiomyocyte proliferation post-MI To study whether exogenous delivery PSAT1 in neonatal rat ventricular CMs (NRVM) or adult CMs post-MI induces CM cell cycle, we used modRNA delivery approach to globally express the PSAT1 in vitro and in the post-MI hearts as described earlier 10 , 44 , 47 , 48 , 50 - 52