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Divergent activation of a glutathione-tryptophan module by cysteine and hydrogen sulfide enables metabolic recovery from cyanide poisoning in rice - ScienceDirect

The amino acid is liberated upon degradation of the g-Glu-amino acid by the enzyme g-glutamyl cyclotransferase, which generates 5-oxoproline instead of glutamate

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These differences were largely driven by greater weight loss and cardiometabolic improvements (blood pressure, glycemia, lipids) in the tirzepatide arm, and population‐level modelling suggested that, in an eligible U.S