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Additionally, the same authors have demonstrated that phytosterols can suppress ATP-binding cassette transporters G5 and G8 (ABCG5/8), the primary neutral sterol transporter responsible for hepatobiliary and transintestinal phytosterols and cholesterol excretion, through mechanisms such as RNA interference or liver X receptor (LXR) antagonism

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As for L-NAME and/or L-arginine, we noted: L-arginine (100 mg/kg i.p.)–rats: more bleeding, less/no thrombocytopenia