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However, GSSG supplementation up-regulated ( p 0.5) suggested that the DNA methylation and mRNA profiles observed at 1 week of age persisted over time, at least until 15 weeks after the cessation of treatments
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In addition to the direct effects of ascorbate availability on metabolic pathways, the abundance of ascorbate exerts a strong influence on gene expression (Kiddle et al., 2003
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